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Recombinant Mouse Tumor necrosis factor receptor superfamily member 4 (Tnfrsf4), partial (Active)

Recombinant Mouse Tumor necrosis factor receptor superfamily member 4 (Tnfrsf4), partial (Active) — Receptor for TNFSF4/OX40L/GP34. Purity >90%.

SKU: BCACP-000622 Categories: ,
Product SKUBCACP-000622
Product DescriptionRecombinant Mouse Tumor necrosis factor receptor superfamily member 4 (Tnfrsf4) protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 20-211aa. [Accession | P47741].
Uniprot No.P47741
Gene NamesTnfrsf4
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region20-211aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal hFc1-tagged
Molecular weight50.2 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Anti-TACSTD2 recombinant antibody at 2 μg/mL can bind Human TACSTD2. The EC50 is 11.22-13.11 ng/mL.;TACSTD2 Recombinant Monoclonal Antibody captured on Protein A Chip can bind Human TACSTD2 with an affinity constant of 2.52 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesTumor necrosis factor receptor superfamily member 4; OX40 antigen; OX40L receptor; CD antigen CD134

Function

Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)
Tissue Specificity: Expressed in CD4(+) T-cells and in T-helper Th17 cells (at protein level)

Product Specifications

Recombinant Mouse Tumor necrosis factor receptor superfamily member 4 (Tnfrsf4), partial (Active) is a recombinant protein from Mus musculus (Mouse), expressed in Mammalian cell, covering amino acids 20-211aa, with C-terminal hFc1-tagged tag, molecular weight 50.2 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity (By similarity)

Subcellular Location

Membrane (Single-pass type I membrane protein)

Tissue Specificity

Expressed in CD4(+) T-cells and in T-helper Th17 cells (at protein level)

Subunit

Interacts with TRAF2, TRAF3 and TRAF5

Gene: Tnfrsf4  |  Organism: Mus musculus  |  Synonyms: OX40 antigen; OX40L receptor

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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