Recombinant Human Beta-defensin 104 protein (DEFB104A), Homo sapiens (Human), E.Coli, Tag-Free, 6.0 kDa, purity >>98% as determined by SDS-PAGE.

Recombinant Human Beta-defensin 104 protein (DEFB104A)

Recombinant Human Beta-defensin 104 protein (DEFB104A) — Has antimicrobial activity. Purity >98%.

SKU: BCACP-000890 Category:
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Product SKUBCACP-000890
Product DescriptionRecombinant Human Beta-defensin 104 protein (DEFB104A) protein is expressed from E.Coli with Tag-Free. It contains 23-72aa. [Accession | Q8WTQ1].
Uniprot No.Q8WTQ1
Gene NamesDEFB104A
Purity>98% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region23-72aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight6.0 kDa
ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesBD 4; BD-4; BD4; beta 104; beta 4 Defensin; Beta defensin 4; Beta-defensin 104; Beta-defensin 4; D104A_HUMAN; DEFB-4; DEFB104B; Defensin; Defensin beta 104; Defensin beta 4 precursor; hBD 4; hBD-4; hBD4

Function

Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested

Product Specifications

Recombinant Human Beta-defensin 104 protein (DEFB104A) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 23-72aa, with Tag-Free tag, molecular weight 6.0 kDa, purity >98% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103

Subcellular Location

Secreted

Tissue Specificity

High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested

Gene: DEFB104A, DEFB104B  |  Organism: Homo sapiens  |  Synonyms: Beta-defensin 4; Defensin, beta 104

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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