Recombinant Mouse Desmocollin-3 (Dsc3) Protein, Mus musculus (Mouse), in vitro E.coli expression system, N-terminal 10xHis-tagged, 86.3kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Desmocollin-3 (Dsc3) Protein

Recombinant Mouse Desmocollin-3 (Dsc3) Protein — A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Purity >85%.

SKU: BCRECP-00283TM Category:
Online Inquiry →

Product Specifications

Uniprot No.P55850
Gene NamesDsc3
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region136-896aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged
Molecular weight86.3kDa
ActivityNot Test
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Required for cell-cell adhesion in the epidermis, as a result required for the maintenance of the dermal cohesion and the dermal barrier function. Required for cell-cell adhesion of epithelial cell layers surrounding the telogen hair club, as a result plays an important role in telogen hair shaft anchorage.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein); Cell junction, desmosome; Cytoplasm
Tissue Specificity: Expressed in the basal layers of epidermal stratified epithelia from birth (at protein level)

Product Specifications

Recombinant Mouse Desmocollin-3 (Dsc3) Protein is a recombinant protein from Mus musculus (Mouse), expressed in in vitro E.coli expression system, covering amino acids 136-896aa, with N-terminal 10xHis-tagged tag, molecular weight 86.3kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion (PubMed:38395410). Required for cell-cell adhesion in the epidermis, as a result required for the maintenance of the dermal cohesion and the dermal barrier function (PubMed:18682494). Required for cell-cell adhesion of epithelial cell layers surrounding the telogen hair club, as a result plays an important role in telogen hair shaft anchorage (PubMed:18682494). Essential for successful completion of embryo compaction and development beyond the 8-cell stage (PubMed:16418220)

Subcellular Location

Cell membrane (Single-pass type I membrane protein); Cell junction, desmosome; Cytoplasm

Tissue Specificity

Expressed in the basal layers of epidermal stratified epithelia from birth (at protein level)

Subunit

May form homodimers (By similarity). Interacts with DSG1; there is evidence to suggest that the interaction promotes cell-cell adhesion of keratinocytes (By similarity)

Gene: Dsc3  |  Organism: Mus musculus
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

Shopping Cart
Scroll to Top