Recombinant Interleukin 18 Receptor 1 (IL18R1), 293F cell, Fc, 6×His tag at the C-terminus, 80 kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Interleukin 18 Receptor 1 (IL18R1)

Recombinant Interleukin 18 Receptor 1 (IL18R1) — Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Purity >90%.

SKU: BCRETP-000005 Categories: ,
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Product Specifications

Product SkuBCRETP-000005
Product DescriptionRecombinant Interleukin 18 Receptor 1 (IL18R1) is expressed from HEK293F with Fc tag at the C-Terminus. It contains 20-329aa. [Accession | Q13478].
Uniprot No.Q13478
SynonymsCDw218a; CD218a; IL18-R1; IL-1Rrp; IL1RRP; CD218 antigen-like family member A; IL1 receptor-related protein
PurityGreater than 90% as determined by SDS-PAGE.
Expression System293F cell
Expression Region20-329aa
Tag InfoFc, 6×His tag at the C-terminus
Molecular weight80 kDa
EndotoxinLess than 1.0 EU/μg as determined by LAL method.

Function

Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3.

Product Specifications

Recombinant Interleukin 18 Receptor 1 (IL18R1) is a recombinant protein, expressed in 293F cell, covering amino acids 20-329aa, with Fc, 6×His tag at the C-terminus tag, molecular weight 80 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B (PubMed:14528293, PubMed:25261253, PubMed:25500532, PubMed:37993714, PubMed:8626725). Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (By similarity)

Gene: IL18R1  |  Organism: Homo sapiens

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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