Recombinant Human Transient receptor potential cation channel subfamily V member 2 (TRPV2)-Detergent Protein, Homo sapiens (Human), Mammalian cell, N-terminal 10xHis-tagged and C-terminal Twin-Strep-tagged, 90.5kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Transient receptor potential cation channel subfamily V member 2 (TRPV2)-Detergent Protein

Recombinant Human Transient receptor potential cation channel subfamily V member 2 (TRPV2)-Detergent Protein — Calcium-permeable, non-selective cation channel. Purity >85%.

SKU: BCRECP-00521TM Category:
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Product Specifications

Uniprot No.Q9Y5S1
Gene NamesTRPV2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region1-764aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged and C-terminal Twin-Strep-tagged
Molecular weight90.5kDa
ActivityNot Test
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Calcium-permeable, non-selective cation channel. Seems to be regulated, at least in part, by growth factors, such as IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein); Cytoplasm; Melanosome

Product Specifications

Recombinant Human Transient receptor potential cation channel subfamily V member 2 (TRPV2)-Detergent Protein is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 1-764aa, with N-terminal 10xHis-tagged and C-terminal Twin-Strep-tagged tag, molecular weight 90.5kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Calcium-permeable, non-selective cation channel (PubMed:10201375). Seems to be regulated, at least in part, by growth factors, such as IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells (By similarity)

Subcellular Location

Cell membrane (Multi-pass membrane protein); Cytoplasm; Melanosome

Subunit

Homotetramer (By similarity). Interacts with a cAMP-dependent protein kinase type II regulatory subunit (PRKAR2A or PRKAR2B) and ACBD3 (By similarity). Interacts with SLC50A1; the interaction probably occurs intracellularly and depends on TRPV2 N-glycosylation (By similarity)

Gene: TRPV2  |  Organism: Homo sapiens  |  Synonyms: Osm-9-like TRP channel 2; Vanilloid receptor-like protein 1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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