Recombinant Human Microtubule-Associated Protein Tau(MAPT), 293F cell, C-6His, 65 kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Microtubule-Associated Protein Tau(MAPT)

Recombinant Human Microtubule-Associated Protein Tau(MAPT) — Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Purity >90%.

SKU: BCRETP-000029 Category:
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Product Specifications

Product SkuBCRETP-000029
Product DescriptionRecombinant Human Microtubule-Associated Protein Tau(MAPT) is expressed from HEK293F with His tag at the C-Terminus. It contains 1-441aa. [Accession | P10636].
Uniprot No.P10636
SynonymsTAU, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, Microtubule-associated protein tau
PurityGreater than 90% as determined by SDS-PAGE.
Expression System293F cell
Expression Region1-441aa
Tag InfoC-6His
Molecular weight65 kDa
EndotoxinLess than 1.0 EU/μg as determined by LAL method.

Function

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome.

Product Specifications

Recombinant Human Microtubule-Associated Protein Tau(MAPT) is a recombinant protein, expressed in 293F cell, covering amino acids 1-441aa, with C-6His tag, molecular weight 65 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity (PubMed:21985311). The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both (PubMed:21985311, PubMed:32961270). Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization

Gene: MAPT  |  Organism: Homo sapiens

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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