Recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B), partial, Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 20.8kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B), partial

Recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B), partial — Receptor for the Fc region of immunoglobulins gamma. Purity >95%.

SKU: BCRECP-000653 Categories: ,
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Product Specifications

Product SkuBCRECP-000653
Product DescriptionRecombinant Human Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B) Protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 17-200aa. [Accession | O75015].
Uniprot No.O75015
Gene NamesFCGR3B
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region17-200aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight20.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG.

Biological Context

Subcellular Location: Cell membrane (Lipid-anchor, GPI-anchor); Secreted
Tissue Specificity: Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils

Product Specifications

Recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-B (FCGR3B), partial is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 17-200aa, with C-terminal 10xHis-tagged tag, molecular weight 20.8kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils

Subcellular Location

Cell membrane (Lipid-anchor, GPI-anchor); Secreted

Tissue Specificity

Expressed specifically by polymorphonuclear leukocytes (neutrophils). Also expressed by stimulated eosinophils

Subunit

Monomer. Interacts with INPP5D/SHIP1 (By similarity). Interacts with the Fc region of IgGs with a preference for IgG1 and IgG3 isotypes

Gene: FCGR3B  |  Organism: Homo sapiens  |  Synonyms: Fc-gamma RIII-beta; FcR-10; IgG Fc receptor III-1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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