Recombinant Human Peroxisome proliferator-activated receptor delta (PPARD), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 49.8kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Peroxisome proliferator-activated receptor delta (PPARD), partial

Recombinant Human Peroxisome proliferator-activated receptor delta (PPARD), partial — Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues. Purity >85%.

SKU: BCRECP-001424 Category:
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Product Specifications

Product SkuBCRECP-001424
Product DescriptionRecombinant Human Peroxisome proliferator-activated receptor delta (PPARD) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 165-441aa. [Accession | Q03181].
Uniprot No.Q03181
Gene NamesPPARD
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region165-441aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight49.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid.

Biological Context

Subcellular Location: Nucleus
Tissue Specificity: Ubiquitous with maximal levels in placenta and skeletal muscle

Product Specifications

Recombinant Human Peroxisome proliferator-activated receptor delta (PPARD), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 165-441aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 49.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues (PubMed:35675826). Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand

Subcellular Location

Nucleus

Tissue Specificity

Ubiquitous with maximal levels in placenta and skeletal muscle

Subunit

Heterodimer with the retinoid X receptor. Interacts (via domain NR LBD) with CRY1 and CRY2 in a ligand-dependent manner (By similarity)

Gene: PPARD  |  Organism: Homo sapiens  |  Synonyms: NUCI; Nuclear hormone receptor 1; Nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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