Recombinant Human Small ribosomal subunit protein uS5 (RPS2), Homo sapiens (Human), E.coli, C-terminal 6xHis-tagged, 38.1kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Small ribosomal subunit protein uS5 (RPS2)

Recombinant Human Small ribosomal subunit protein uS5 (RPS2) — Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Purity >90%.

SKU: BCRECP-001563 Category:
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Product Specifications

Product SkuBCRECP-001563
Product DescriptionRecombinant Human Small ribosomal subunit protein uS5 (RPS2) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 2-293aa. [Accession | P15880].
Uniprot No.P15880
Gene NamesRPS2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region2-293aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight38.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Biology

Function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.

Biological Context

Subcellular Location: Cytoplasm; Nucleus, nucleolus

Product Specifications

Recombinant Human Small ribosomal subunit protein uS5 (RPS2) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 2-293aa, with C-terminal 6xHis-tagged tag, molecular weight 38.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (PubMed:23636399). The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (PubMed:23636399). The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:23636399). Plays a role in the assembly and function of the 40S ribosomal subunit (By similarity). Mutations in this protein affects the control of translational fidelity (By similarity). Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity)

Subcellular Location

Cytoplasm; Nucleus, nucleolus

Subunit

Component of the small ribosomal subunit (PubMed:23636399). Interacts with zinc finger protein ZNF277 (via zinc-finger domains); the interaction is direct; the interaction is extra-ribosomal (PubMed:30530495). Interaction with ZNF277 competes with the binding of RPS2 to protein arginine methyltransferase PRMT3 (PubMed:30530495). Interacts with PRMT3 (PubMed:27697862). Interacts with PDCD2; the interaction is direct, occurs cotranslationally, and serves to chaperone uS5 to assembly sites in the nucleus (PubMed:33245768). Interacts with PDCD2L; for chaperone function of PDC2L (PubMed:27697862). Interacts (when monoubiquitinated at Lys-54 and Lys-58) with RIOK3 (PubMed:39947182, PubMed:39947183)

Gene: RPS2  |  Organism: Homo sapiens  |  Synonyms: 40S ribosomal protein S2; 40S ribosomal protein S4; Protein LLRep3
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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