Function
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
Biological Context
Subcellular Location: Microsome membrane (Lipid-anchor, GPI-anchor)
Tissue Specificity: Mostly in endothelial cells
Product Specifications
Recombinant Human Tissue factor pathway inhibitor (TFPI), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 29-282aa, with C-terminal 10xHis-tagged tag, molecular weight 31.9kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
