Recombinant Mouse Stathmin-2 (Stmn2)

Recombinant Mouse Stathmin-2 (Stmn2) — Regulator of microtubule stability. Purity >95%.

SKU: BCRECP-004500 Category:

Product Specifications

Product SkuBCRECP-004500
Product DescriptionRecombinant Mouse Stathmin-2 (Stmn2) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 1-179aa. [Accession | P55821].
Uniprot No.P55821
Gene NamesStmn2
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-179aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 6xHis-tagged
Molecular weight27.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone.

Biological Context

Subcellular Location: Cytoplasm; Cytoplasm, perinuclear region; Cell projection, growth cone; Cell projection, axon; Membrane (Peripheral membrane protein); Endosome; Golgi apparatus; Cell projection, lamellipodium
Tissue Specificity: Neuron specific

Product Specifications

Recombinant Mouse Stathmin-2 (Stmn2) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 1-179aa, with C-terminal 6xHis-tagged tag, molecular weight 27.7kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone

Subcellular Location

Cytoplasm; Cytoplasm, perinuclear region; Cell projection, growth cone; Cell projection, axon; Membrane (Peripheral membrane protein); Endosome; Golgi apparatus; Cell projection, lamellipodium

Tissue Specificity

Neuron specific

Subunit

Interacts with ITM2C. Interacts with MAPK8. Interacts with KIFBP. Interacts (via the N-terminal region) with CIB1 (via C-terminal region); the interaction is direct, occurs in a calcium-dependent manner and attenuates the neurite outgrowth inhibition of STMN2

Gene: Stmn2  |  Organism: Mus musculus  |  Synonyms: Superior cervical ganglion-10 protein

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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