Recombinant Mouse Synaptic vesicle glycoprotein 2A (Sv2a), partial, Mus musculus (Mouse), E.coli, C-terminal 6xHis-tagged, 22.1kDa, purity >90% as determined by SDS-PAGE.

Recombinant Mouse Synaptic vesicle glycoprotein 2A (Sv2a), partial

Recombinant Mouse Synaptic vesicle glycoprotein 2A (Sv2a), partial — (Microbial infection) Receptor for C. Purity >90%.

SKU: BCRECP-004516 Category:
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Product Specifications

Product SkuBCRECP-004516
Product DescriptionRecombinant Mouse Synaptic vesicle glycoprotein 2A (Sv2a) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 469-598aa. [Accession | Q9JIS5].
Uniprot No.Q9JIS5
Gene NamesSv2a
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region469-598aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 6xHis-tagged
Molecular weight22.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

(Microbial infection) Receptor for C.botulinum neurotoxin type E (BoNT/E); the toxin probably binds via extracellular loop 4. It probably requires glycosylation of Asn-573.

Biological Context

Subcellular Location: Presynapse; Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane (Multi-pass membrane protein)
Tissue Specificity: Expressed in conventional synapses and cone ribbon synapses in the retina (at protein level). Expressed in diaphragm motor nerve terminals (at protein level). Expressed in hippocampus neurons (at protein level)

Product Specifications

Recombinant Mouse Synaptic vesicle glycoprotein 2A (Sv2a), partial is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 469-598aa, with C-terminal 6xHis-tagged tag, molecular weight 22.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

(Microbial infection) Receptor for C.botulinum neurotoxin type E (BoNT/E); the toxin probably binds via extracellular loop 4 (PubMed:18815274). It probably requires glycosylation of Asn-573 (PubMed:18815274)

Subcellular Location

Presynapse; Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane (Multi-pass membrane protein)

Tissue Specificity

Expressed in conventional synapses and cone ribbon synapses in the retina (at protein level) (PubMed:12687700). Expressed in diaphragm motor nerve terminals (at protein level) (PubMed:16543415). Expressed in hippocampus neurons (at protein level) (PubMed:18815274)

Subunit

(Microbial infection) Interacts with C.botulinum neurotoxin type A (BoNT/A, botA)

Gene: Sv2a  |  Organism: Mus musculus  |  Synonyms: Calcium regulator SV2A
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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