Recombinant Mouse Angiopoietin-like protein 8 (Angptl8) (H40A,Q44A,Q47A)

Recombinant Mouse Angiopoietin-like protein 8 (Angptl8) (H40A,Q44A,Q47A) — Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. Purity >90%.

SKU: BCRECP-002093 Category:

Product Specifications

Product SkuBCRECP-002093
Product DescriptionRecombinant Mouse Angiopoietin-like protein 8 (Angptl8) (H40A,Q44A,Q47A) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 16-198aa(H40A,Q44A,Q47A). [Accession | Q8R1L8].
Uniprot No.Q8R1L8
Gene NamesAngptl8
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region16-198aa(H40A,Q44A,Q47A)
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 6xHis-tagged
Molecular weight21.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state.

Product Specifications

Recombinant Mouse Angiopoietin-like protein 8 (Angptl8) (H40A,Q44A,Q47A) — Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. Purity >90%. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577, PubMed:24043787). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (PubMed:24043787). According to a report, may act by promoting ANGPTL3 cleavage (PubMed:23150577). According to another study, not required for cleavage of ANGPTL3 (PubMed:24043787)

Subcellular Location

Secreted

Tissue Specificity

Expressed in liver and fat. Enriched in white and brown adipose tissues

Subunit

Interacts with ANGPTL3

Gene: Angptl8  |  Organism: Mus musculus  |  Synonyms: Betatrophin; Lipasin; Refeeding-induced fat and liver protein
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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