Recombinant Mouse COMM domain-containing protein 9 (Commd9), Mus musculus (Mouse), E.coli, C-terminal 6xHis-tagged, 28.8kDa, purity >90% as determined by SDS-PAGE.

Recombinant Mouse COMM domain-containing protein 9 (Commd9)

Recombinant Mouse COMM domain-containing protein 9 (Commd9) — Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex. Purity >90%.

SKU: BCRECP-002415 Category:
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Product Specifications

Product SkuBCRECP-002415
Product DescriptionRecombinant Mouse COMM domain-containing protein 9 (Commd9) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 1-198aa. [Accession | Q8K2Q0].
Uniprot No.Q8K2Q0
Gene NamesCommd9
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-198aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 6xHis-tagged
Molecular weight28.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Biology

Function

Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B.

Biological Context

Subcellular Location: Nucleus; Cytoplasmic vesicle

Product Specifications

Recombinant Mouse COMM domain-containing protein 9 (Commd9) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 1-198aa, with C-terminal 6xHis-tagged tag, molecular weight 28.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (By similarity). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (By similarity). May down-regulate activation of NF-kappa-B (By similarity). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (By similarity)

Subcellular Location

Nucleus; Cytoplasmic vesicle

Subunit

Component of the commander complex consisting of the CCC subcomplex and the retriever subcomplex (By similarity). Component of the CCC (COMMD/CCDC22/CCDC93) subcomplex consisting of COMMD1, COMMD2, COMMD3, COMMD4, COMMD5, COMMD6, COMMD7, COMMD8, COMMD9, COMMD10, CCDC22 and CCDC93; within the complex forms a heterodimer with COMMD7 (By similarity). Interacts with RELB and NFKB1/p105 (By similarity). Interacts with CCDC22, CCDC93, SCNN1B, CUL1 (By similarity)

Gene: Commd9  |  Organism: Mus musculus

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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