Compare BioCrest Sci Osteopontin (SPP1/OPN) recombinant proteins by species, sequence region, expression system, tag, purity and activity status. The catalog includes human and mouse proteins produced in E. coli, yeast and mammalian cells, with His-tagged, Fc-tagged and active options.
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Find the Right Osteopontin / SPP1 Protein
Osteopontin is encoded by the SPP1 gene and is also known as OPN, secreted phosphoprotein 1, bone sialoprotein 1 and uropontin. Catalog products can differ substantially in species, sequence coverage, expression system and tag configuration. Select the SKU that matches the intended assay rather than treating all SPP1 preparations as interchangeable.
- Species: choose human or mouse according to the biological system and assay design.
- Sequence coverage: compare full mature-region and partial constructs before ordering.
- Expression system: E. coli, yeast and mammalian-cell products may differ in folding and post-translational characteristics.
- Tag: available formats include N- or C-terminal His tags, human Fc and His/Myc combinations.
- Functional work: use an active-designated product only after reviewing the product-specific activity method and supporting documentation.
Osteopontin (SPP1) Recombinant Protein Comparison
The table includes the ten current Osteopontin protein results verified in the BioCrest Sci catalog. ACP5 products that merely mention osteopontin in their biological description are excluded.
| Species | Sequence region | Expression system | Tag | Purity | Activity | SKU | Product |
|---|---|---|---|---|---|---|---|
| Human | 17–300 aa | Yeast | N-terminal 6×His | See product page | Not stated | BCACP-654138 | View product |
| Human | 169–314 aa, partial | E. coli | C-terminal 6×His | See product page | Not stated | BCACP-961860 | View product |
| Human | 17–167 aa, partial | E. coli | N-terminal 10×His | See product page | Not stated | BCACP-697128 | View product |
| Human | 17–168 aa, partial | E. coli | N-terminal 6×His | See product page | Not stated | BCACP-590355 | View product |
| Human | 17–314 aa | Mammalian cell | C-terminal 10×His | >95% by SDS-PAGE | Product designated Active; review assay data | BCACP-000583 | View product |
| Mouse | 17–290 aa, partial | Mammalian cell | C-terminal 10×His | See product page | Not stated | BCACP-796828 | View product |
| Mouse | 17–290 aa, partial | Mammalian cell | C-terminal human Fc | ≥95% by SDS-PAGE | Not stated | BCACP-610193 | View product |
| Mouse | 17–290 aa, partial | E. coli | C-terminal 6×His | ≥85% by SDS-PAGE | Not stated | BCACP-890285 | View product |
| Mouse | 17–290 aa, partial | E. coli | N-terminal 10×His; C-terminal Myc | See product page | Not stated | BCACP-611978 | View product |
| Mouse | 17–290 aa, partial | Yeast | N-terminal 6×His | >90% by SDS-PAGE | Contact for bioactivity data | BCRECP-004474 | View product |
Need help choosing a construct? Send the required species, application, preferred expression system, sequence region and tag through the online inquiry form.
Human Osteopontin Recombinant Proteins
Human SPP1 options include yeast-expressed and E. coli-expressed His-tagged proteins with different sequence regions, plus a mammalian-cell-expressed active-designated product covering amino acids 17–314. Compare sequence coverage carefully when selecting between a mature-region protein and a partial construct.
Mouse Osteopontin Recombinant Proteins
Mouse Spp1 options cover amino acids 17–290 and include E. coli, yeast and mammalian-cell expression. Available tag configurations include C-terminal 6×His, C-terminal 10×His, human Fc, and an N-terminal 10×His/C-terminal Myc combination.
How to Select an Osteopontin Protein
- Confirm the target name. Osteopontin, SPP1 and OPN refer to the same core target; avoid confusing SPP1 with proteins that only interact with or dephosphorylate osteopontin.
- Match the species. Choose human or mouse based on the experimental system.
- Check sequence boundaries. The catalog includes different human partial constructs as well as broader sequence coverage.
- Choose the expression system. Consider whether bacterial, yeast or mammalian expression is appropriate for the downstream assay.
- Select the tag configuration. Tag position and format can affect immobilization, detection and functional studies.
- Review product-specific QC. Confirm purity, activity, formulation, storage and available lot documentation on the selected SKU.
Frequently Asked Questions
Are Osteopontin, SPP1 and OPN the same protein target?
SPP1 is the gene symbol for osteopontin, which is also commonly abbreviated OPN. Product naming may use any of these terms, so the species, accession and sequence region should also be checked.
Should I choose full-region or partial Osteopontin?
The answer depends on the assay and epitope or domain requirement. Review the listed amino-acid boundaries and do not assume that partial constructs are interchangeable with broader sequence coverage.
When should I choose mammalian-cell-expressed SPP1?
Mammalian expression may be relevant when native-like processing or post-translational characteristics matter. E. coli or yeast products may be suitable for other binding, detection or immunoassay workflows. Selection should be based on the experiment.
Does every Osteopontin product have biological activity data?
No. Biological activity is SKU-specific. Only treat a product as activity tested when an appropriate method and result are explicitly provided on the product page, datasheet or Certificate of Analysis.
Can BioCrest Sci produce another SPP1 construct?
If the catalog options do not match the required sequence, tag, expression system or scale, submit the project through the custom protein expression service.
Request Osteopontin / SPP1 Price and Availability
Include the SKU, quantity, delivery country, intended application and any purity, activity, tag or documentation requirements. BioCrest Sci will confirm current pack sizes, pricing, availability and estimated dispatch timing.
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For research use only. Product specifications and availability are subject to confirmation on the individual product page and current quotation.