Mouse anti-Human sapiens (Human) SH3GL1 Monoclonal Antibody

Mouse anti-Human sapiens (Human) SH3GL1 Monoclonal Antibody — Implicated in endocytosis.

SKU: BCREC-000521MA Category:

Product Specifications

Uniprot No.Q99961
Target NamesSH3GL1
Species ReactivityMouse
ImmunogenRecombinant Human SH3GL1 protein
Immunogen SpeciesHomo sapiens (Human)
ConjugateNon-conjugated
IsotypeMouse IgG1
ClonalityMonoclonal
ApplicationsELISA, WB, FC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

Implicated in endocytosis. In a first step mediates neck formation during ultrafast endocytosis and function at a second step to aid in the removal of clathrin coats from the regenerated vesicles. May recruit other proteins to membranes with high curvature.

Biological Context

Subcellular Location: Cytoplasm; Early endosome membrane (Peripheral membrane protein); Cell projection, podosome
Tissue Specificity: Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus
Disease Association: [In some cases of acute leukemia, a translocation results in the formation of a KMT2A/MLL1-EEN fusion gene]

Product Specifications

Mouse anti-Human sapiens (Human) SH3GL1 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

Applications: ELISA, WB, FC

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Implicated in endocytosis. In a first step mediates neck formation during ultrafast endocytosis and function at a second step to aid in the removal of clathrin coats from the regenerated vesicles (By similarity). May recruit other proteins to membranes with high curvature (By similarity)

Subcellular Location

Cytoplasm; Early endosome membrane (Peripheral membrane protein); Cell projection, podosome

Disease Association

[In some cases of acute leukemia, a translocation results in the formation of a KMT2A/MLL1-EEN fusion gene]

Tissue Specificity

Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus

Subunit

Interacts with ARC (By similarity). Interacts with SYNJ1 and DNM1. Interacts with PDCD6IP. Interacts with BIN2

Gene: SH3GL1  |  Organism: Homo sapiens  |  Synonyms: EEN fusion partner of MLL; Endophilin-2; Extra eleven-nineteen leukemia fusion gene protein; SH3 domain protein 2B; SH3 domain-containing GRB2-like protein 1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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