Function
(Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use.
Biological Context
Subcellular Location: Secreted
Tissue Specificity: Expressed by the liver and secreted in plasma
Disease Association: Atransferrinemia (ATRAF) : A rare autosomal recessive disorder characterized by abnormal synthesis of transferrin leading to iron overload and microcytic hypochromic anemia. [The disease is caused by variants affecting the gene represented in this entry]
Product Specifications
Mouse anti-Human TF Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications. Explore more Antibody products →
