Recombinant Bovine Cation-dependent mannose-6-phosphate receptor (M6PR) Protein, Bos taurus (Bovine), in vitro E.coli expression system, N-terminal 10xHis-tagged, 30.8kDa, purity >85% as determined by SDS-PAGE.

Recombinant Bovine Cation-dependent mannose-6-phosphate receptor (M6PR) Protein

Recombinant Bovine Cation-dependent mannose-6-phosphate receptor (M6PR) Protein — Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Purity >85%.

SKU: BCRECP-00242TM Category:
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Product Specifications

Uniprot No.P11456
Gene NamesM6PR
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region29-279aa
SpeciesBos taurus (Bovine)
Tag InfoN-terminal 10xHis-tagged
Molecular weight30.8kDa
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

Biological Context

Subcellular Location: Lysosome membrane (Single-pass type I membrane protein)

Product Specifications

Recombinant Bovine Cation-dependent mannose-6-phosphate receptor (M6PR) Protein is a recombinant protein from Bos taurus (Bovine), expressed in in vitro E.coli expression system, covering amino acids 29-279aa, with N-terminal 10xHis-tagged tag, molecular weight 30.8kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex

Subcellular Location

Lysosome membrane (Single-pass type I membrane protein)

Subunit

Homodimer. Interacts with GGA1, GGA2 and GGA3 (By similarity)

Gene: M6PR  |  Organism: Bos taurus  |  Synonyms: 46 kDa mannose 6-phosphate receptor

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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