Recombinant Escherichia coli Probable phosphatidylethanolamine transferase Mcr-1 (mcr1) Protein, Escherichia coli, in vitro E.coli expression system, N-terminal 6xHis-SUMO-tagged, 76.1kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Escherichia coli Probable phosphatidylethanolamine transferase Mcr-1 (mcr1) Protein

Recombinant Escherichia coli Probable phosphatidylethanolamine transferase Mcr-1 (mcr1) Protein — Probably catalyzes the addition of a phosphoethanolamine moiety to lipid A. Purity >90%.

SKU: BCRECP-00630TM Categories: ,
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Product Specifications

Uniprot No.A0A0R6L508
Gene Namesmcr1
PurityGreater than 90% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region1-541aa
SpeciesEscherichia coli
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight76.1kDa
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Probably catalyzes the addition of a phosphoethanolamine moiety to lipid A. Phosphoethanolamine modification of lipid A confers polymyxin resistance. Confers resistance to polymyxin-type antibiotics such as colistin; in the E.coli strain W3110.

Biological Context

Subcellular Location: Cell inner membrane (Multi-pass membrane protein)

Product Specifications

Recombinant Escherichia coli Probable phosphatidylethanolamine transferase Mcr-1 (mcr1) Protein is a recombinant protein from Escherichia coli, expressed in in vitro E.coli expression system, covering amino acids 1-541aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 76.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Probably catalyzes the addition of a phosphoethanolamine moiety to lipid A (PubMed:26603172, PubMed:29079699). Phosphoethanolamine modification of lipid A confers polymyxin resistance (PubMed:26603172). Confers resistance to polymyxin-type antibiotics such as colistin; in the E.coli strain W3110 (PubMed:26603172)

Subcellular Location

Cell inner membrane (Multi-pass membrane protein)

Subunit

Monomer

Gene: mcr1  |  Organism: Escherichia coli  |  Synonyms: Polymyxin resistance protein MCR-1
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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

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Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

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Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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