Recombinant Human 5-hydroxytryptamine receptor 2A (HTR2A) Protein, Homo sapiens (Human), in vitro E.coli expression system, N-terminal 10xHis-tagged, 58.7kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human 5-hydroxytryptamine receptor 2A (HTR2A) Protein

Recombinant Human 5-hydroxytryptamine receptor 2A (HTR2A) Protein — recombinant protein from Homo sapiens (Human), expressed in in vitro E.coli expression system. Purity >85%.

SKU: BCRECP-00295TM Category:
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Product Specifications

Uniprot No.P28223
Gene NamesHTR2A
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region1-471aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight58.7kDa
ActivityNot Test
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

(Microbial infection) Acts as a receptor for human JC polyomavirus/JCPyV.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein); Cell projection, dendrite; Cell projection, axon; Cytoplasmic vesicle; Membrane, caveola; Presynapse
Tissue Specificity: Detected in brain cortex (at protein level). Detected in blood platelets

Product Specifications

Recombinant Human 5-hydroxytryptamine receptor 2A (HTR2A) Protein is a recombinant protein from Homo sapiens (Human), expressed in in vitro E.coli expression system, covering amino acids 1-471aa, with N-terminal 10xHis-tagged tag, molecular weight 58.7kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not Test

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Acts as a receptor for human JC polyomavirus/JCPyV

Subcellular Location

Cell membrane (Multi-pass membrane protein); Cell projection, dendrite; Cell projection, axon; Cytoplasmic vesicle; Membrane, caveola; Presynapse

Tissue Specificity

Detected in brain cortex (at protein level). Detected in blood platelets

Subunit

Interacts (via C-terminus) with MPDZ and PATJ (PubMed:11150294, PubMed:14988405). May interact (via C-terminus) with MPP3, PRDX6, DLG4, DLG1, CASK, APBA1 and MAGI2 (PubMed:14988405). Interacts with GRM2 and DRD2; this may affect signaling (PubMed:18297054, PubMed:21645528, PubMed:22300836)

Gene: HTR2A  |  Organism: Homo sapiens  |  Synonyms: Serotonin receptor 2A
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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