Recombinant Human Synaptophysin (SYP) Protein, Homo sapiens (Human), in vitro E.coli expression system, N-terminal 10xHis-tagged, 39.9kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Synaptophysin (SYP) Protein

Recombinant Human Synaptophysin (SYP) Protein — Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Purity >85%.

SKU: BCRECP-00290TM Category:
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Product Specifications

Uniprot No.P08247
Gene NamesSYP
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region1-313aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight39.9kDa
ActivityNot Test
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.

Biological Context

Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane (Multi-pass membrane protein); Synapse, synaptosome
Tissue Specificity: Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3. Expressed in the putamen (at protein level)
Disease Association: Intellectual developmental disorder, X-linked 96 (XLID96) : A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Synaptophysin (SYP) Protein is a recombinant protein from Homo sapiens (Human), expressed in in vitro E.coli expression system, covering amino acids 1-313aa, with N-terminal 10xHis-tagged tag, molecular weight 39.9kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not Test

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity)

Subcellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane (Multi-pass membrane protein); Synapse, synaptosome

Disease Association

Intellectual developmental disorder, X-linked 96 (XLID96) : A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Expressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3 (PubMed:8838578). Expressed in the putamen (at protein level) (PubMed:17296554)

Subunit

Homohexamer or homotetramer. Interacts with SRCIN1 (PubMed:18662323). Interacts with VAMP2; the interaction is inhibited by interaction of VAPM2 with SEPT8 (By similarity)

Gene: SYP  |  Organism: Homo sapiens  |  Synonyms: Major synaptic vesicle protein p38
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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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