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Recombinant Human Acetyl-coenzyme A synthetase 2-like, mitochondrial (ACSS1)

Recombinant Human Acetyl-coenzyme A synthetase 2-like, mitochondrial (ACSS1) — Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Purity >90%.

SKU: BCRECP-000023 Categories: ,

Product Specifications

Product SkuBCRECP-000023
Product DescriptionRecombinant Human Acetyl-coenzyme A synthetase 2-like, mitochondrial (ACSS1) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 38-689aa. [Accession | Q9NUB1].
Uniprot No.Q9NUB1
Gene NamesACSS1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region38-689aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight75.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity.

Biological Context

Subcellular Location: Mitochondrion matrix

Product Specifications

Recombinant Human Acetyl-coenzyme A synthetase 2-like, mitochondrial (ACSS1) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 38-689aa, with N-terminal 6xHis-tagged tag, molecular weight 75.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids (PubMed:16788062). Acetate is the preferred substrate (PubMed:16788062). Can also utilize propionate with a much lower affinity (By similarity). Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (By similarity). Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity)

Subcellular Location

Mitochondrion matrix

Subunit

Interacts with SIRT3

Gene: ACSS1  |  Organism: Homo sapiens  |  Synonyms: Acetate--CoA ligase 2; Acetyl-CoA synthetase 2; Acyl-CoA synthetase short-chain family member 1; Propionate--CoA ligase
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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