Recombinant Human Beta-defensin 104 protein (DEFB104A)

Recombinant Human Beta-defensin 104 protein (DEFB104A) — Has antimicrobial activity. Purity >98%.

SKU: BCACP-000890 Category:
Product SKUBCACP-000890
Product DescriptionRecombinant Human Beta-defensin 104 protein (DEFB104A) protein is expressed from E.Coli with Tag-Free. It contains 23-72aa. [Accession | Q8WTQ1].
Uniprot No.Q8WTQ1
Gene NamesDEFB104A
Purity>98% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region23-72aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight6.0 kDa
ActivityFully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesBD 4; BD-4; BD4; beta 104; beta 4 Defensin; Beta defensin 4; Beta-defensin 104; Beta-defensin 4; D104A_HUMAN; DEFB-4; DEFB104B; Defensin; Defensin beta 104; Defensin beta 4 precursor; hBD 4; hBD-4; hBD4

Function

Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested

Product Specifications

Recombinant Human Beta-defensin 104 protein (DEFB104A) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 23-72aa, with Tag-Free tag, molecular weight 6.0 kDa, purity >98% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103

Subcellular Location

Secreted

Tissue Specificity

High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested

Gene: DEFB104A, DEFB104B  |  Organism: Homo sapiens  |  Synonyms: Beta-defensin 4; Defensin, beta 104

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

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Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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