Function
Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.
Biological Context
Subcellular Location: Secreted
Tissue Specificity: High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested
Product Specifications
Recombinant Human Beta-defensin 104 protein (DEFB104A) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 23-72aa, with Tag-Free tag, molecular weight 6.0 kDa, purity >98% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg.
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.