Recombinant Human C-C motif chemokine 15 protein (CCL15), partial (Active), Homo sapiens (Human), E.Coli, Tag-Free, 7.4 kDa, purity >>98% as determined by SDS-PAGE.
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Recombinant Human C-C motif chemokine 15 protein (CCL15), partial (Active)

Recombinant Human C-C motif chemokine 15 protein (CCL15), partial (Active) — Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Purity >98%.

SKU: BCACP-000734 Categories: ,
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Product SKUBCACP-000734
Product DescriptionRecombinant Human C-C motif chemokine 15 protein (CCL15) protein is expressed from E.Coli with Tag-Free. It contains 46-113aa. [Accession | Q16663].
Uniprot No.Q16663
Gene NamesCCL15
Purity>98% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region46-113aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight7.4 kDa
ActivityFully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesC-C motif chemokine 15; C-C motif chemokine ligand 15; CC chemokine 3; CCL15; CCL15(29-92); CCL15_HUMAN; Chemokine (C C motif) ligand 15; Chemokine CC-2; Chemokine CC2; HCC-2; HCC2; HMRP 2B; HMRP2B; Leukotactin 1; Leukotactin-1; LKN-1; LKN1; Macrophage inflammatory protein 5; MIP 1D; MIP-1 delta; MIP-1D; MIP-5; MIP1 delta; MIP1d; MIP5; MRP 2B; Mrp-2b; Mrp2b; NCC 3; NCC-3; NCC3; New CC chemokine 3; OTTHUMP00000163955; SCYA15; SCYL3; Small inducible cytokine A15; Small inducible cytokine subfamily A (Cys Cys); member 15; Small-inducible cytokine A15; SY15

Function

Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients

Product Specifications

Recombinant Human C-C motif chemokine 15 protein (CCL15), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 46-113aa, with Tag-Free tag, molecular weight 7.4 kDa, purity >98% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the CCL15

Subcellular Location

Secreted

Tissue Specificity

Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients

Subunit

Monomer

Gene: CCL15  |  Organism: Homo sapiens  |  Synonyms: Chemokine CC-2; Leukotactin-1; MIP-1 delta; Macrophage inflammatory protein 5; Mrp-2b; NCC-3; Small-inducible cytokine A15
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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