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Recombinant Human C-C motif chemokine 15 protein (CCL15)

Recombinant Human C-C motif chemokine 15 protein (CCL15) — Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Purity >97%.

SKU: BCACP-000735 Categories: ,
Product SKUBCACP-000735
Product DescriptionRecombinant Human C-C motif chemokine 15 protein (CCL15) protein is expressed from E.Coli with Tag-Free. It contains 22-113aa. [Accession | Q16663].
Uniprot No.Q16663
Gene NamesCCL15
Purity>97% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region22-113aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight10.2 kDa
ActivityFully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1.0-10 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesC-C motif chemokine 15; C-C motif chemokine ligand 15; CC chemokine 3; CCL15; CCL15(29-92); CCL15_HUMAN; Chemokine (C C motif) ligand 15; Chemokine CC-2; Chemokine CC2; HCC-2; HCC2; HMRP 2B; HMRP2B; Leukotactin 1; Leukotactin-1; LKN-1; LKN1; Macrophage inflammatory protein 5; MIP 1D; MIP-1 delta; MIP-1D; MIP-5; MIP1 delta; MIP1d; MIP5; MRP 2B; Mrp-2b; Mrp2b; NCC 3; NCC-3; NCC3; New CC chemokine 3; OTTHUMP00000163955; SCYA15; SCYL3; Small inducible cytokine A15; Small inducible cytokine subfamily A (Cys Cys); member 15; Small-inducible cytokine A15; SY15

Function

Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients

Product Specifications

Recombinant Human C-C motif chemokine 15 protein (CCL15) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 22-113aa, with Tag-Free tag, molecular weight 10.2 kDa, purity >97% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1.0-10 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the CCL15

Subcellular Location

Secreted

Tissue Specificity

Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients

Subunit

Monomer

Gene: CCL15  |  Organism: Homo sapiens  |  Synonyms: Chemokine CC-2; Leukotactin-1; MIP-1 delta; Macrophage inflammatory protein 5; Mrp-2b; NCC-3; Small-inducible cytokine A15
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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