Function
Chemoattractant for eosinophils and basophils. Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils. Also acts as a ligand for CX3C chemokine receptor CX3CR1, inducing cell chemotaxis.
Biological Context
Subcellular Location: Secreted
Tissue Specificity: Ubiquitously expressed at low levels in various tissues including heart and ovary
Product Specifications
Recombinant Human C-C motif chemokine 26 protein (CCL26) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 24-94aa, with Tag-Free tag, molecular weight 8.4 kDa, purity >97% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications. Explore more Chemokine proteins →
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Fully biologically active when compared to standard. The biological activity is determined by its ability to enhance neurite outgrowth of E16?E18 rat embryonic cortical neurons. rHuTAFA?2, immobilized at 6?24 μg/mL on a 96 well plate, is able to significantly enhance neurite outgrowth.
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.