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Recombinant Human C-C motif chemokine 26 protein (CCL26)

Recombinant Human C-C motif chemokine 26 protein (CCL26) — Chemoattractant for eosinophils and basophils. Purity >97%.

SKU: BCACP-000775 Categories: ,
Product SKUBCACP-000775
Product DescriptionRecombinant Human C-C motif chemokine 26 protein (CCL26) protein is expressed from E.Coli with Tag-Free. It contains 24-94aa. [Accession | Q9Y258].
Uniprot No.Q9Y258
Gene NamesCCL26
Purity>97% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region24-94aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight8.4 kDa
ActivityFully biologically active when compared to standard. The biological activity is determined by its ability to enhance neurite outgrowth of E16?E18 rat embryonic cortical neurons. rHuTAFA?2, immobilized at 6?24 μg/mL on a 96 well plate, is able to significantly enhance neurite outgrowth.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesC-C motif chemokine 26; CC chemokine IMAC; CCL 26; CCL26; CCL26_HUMAN; Chemokine (C C motif) ligand 26; chemokine N1; Eotaxin 3; Eotaxin-3; IMAC; Macrophage inflammatory protein 4-alpha; MIP 4a; MIP 4alpha; MIP-4-alpha; MIP4a; MIP4alpha; SCYA 26; SCYA26; Small inducible cytokine A26; Small inducible cytokine subfamily A (Cys Cys) member 26; Small inducible cytokine subfamily A member 26; Small-inducible cytokine A26; Thymic stroma chemokine 1; Thymic stroma chemokine-1; TSC 1; TSC-1; TSC1

Function

Chemoattractant for eosinophils and basophils. Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils. Also acts as a ligand for CX3C chemokine receptor CX3CR1, inducing cell chemotaxis.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Ubiquitously expressed at low levels in various tissues including heart and ovary

Product Specifications

Recombinant Human C-C motif chemokine 26 protein (CCL26) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 24-94aa, with Tag-Free tag, molecular weight 8.4 kDa, purity >97% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Fully biologically active when compared to standard. The biological activity is determined by its ability to enhance neurite outgrowth of E16?E18 rat embryonic cortical neurons. rHuTAFA?2, immobilized at 6?24 μg/mL on a 96 well plate, is able to significantly enhance neurite outgrowth.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Chemoattractant for eosinophils and basophils (PubMed:10415065, PubMed:10488147). Acts as a ligand for C-C chemokine receptor CCR3 which triggers Ca(2+) mobilization in eosinophils (PubMed:10415065, PubMed:10488147, PubMed:11425309). Also acts as a ligand for CX3C chemokine receptor CX3CR1, inducing cell chemotaxis (PubMed:20974991)

Subcellular Location

Secreted

Tissue Specificity

Ubiquitously expressed at low levels in various tissues including heart and ovary

Subunit

Monomer

Gene: CCL26  |  Organism: Homo sapiens  |  Synonyms: CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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