Recombinant Human C-type lectin domain family 9 member A (CLEC9A), partial, Biotinylated (Active), Homo sapiens (Human), Mammalian cell, N-terminal hFc1-Avi-tagged, 50.4 kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Human C-type lectin domain family 9 member A (CLEC9A), partial, Biotinylated (Active)

Recombinant Human C-type lectin domain family 9 member A (CLEC9A), partial, Biotinylated (Active) — Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Purity >90%.

SKU: BCACP-000320 Categories: , ,
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Product SKUBCACP-000320
Product DescriptionRecombinant Human C-type lectin domain family 9 member A (CLEC9A), Biotinylated protein is expressed from Mammalian cell with N-terminal hFc1-Avi-tagged. It contains 57-241aa. [Accession | Q6UXN8].
Uniprot No.Q6UXN8
Gene NamesCLEC9A
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region57-241aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal hFc1-Avi-tagged
Molecular weight50.4 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human ALPP at 2 μg/mL can bind Anti-ALPP/ALPG recombinant antibody . The EC50 is 4.478-5.236 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesC-type lectin domain family 9 member A; CD370; CLEC9A; UNQ9341/PRO34046

Function

Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.

Product Specifications

Recombinant Human C-type lectin domain family 9 member A (CLEC9A), partial, Biotinylated (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 57-241aa, with N-terminal hFc1-Avi-tagged tag, molecular weight 50.4 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPP at 2 μg/mL can bind Anti-ALPP/ALPG recombinant antibody . The EC50 is 4.478-5.236 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner

Gene: CLEC9A  |  Organism: Homo sapiens

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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