Recombinant Human C-X-C motif chemokine 11 protein (CXCL11), Homo sapiens (Human), E.Coli, Tag-Free, 8.3 kDa, purity >>97% as determined by SDS-PAGE.
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Recombinant Human C-X-C motif chemokine 11 protein (CXCL11)

Recombinant Human C-X-C motif chemokine 11 protein (CXCL11) — Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Purity >97%.

SKU: BCACP-000749 Categories: ,
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Product SKUBCACP-000749
Product DescriptionRecombinant Human C-X-C motif chemokine 11 protein (CXCL11) protein is expressed from E.Coli with Tag-Free. It contains 22-94aa. [Accession | O14625].
Uniprot No.O14625
Gene NamesCXCL11
Purity>97% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region22-94aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight8.3 kDa
ActivityFully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using PHA and rHuIL?2 activated human peripheral blood T?lymphocytes is in a concentration range of 30?100 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative Namesb R1; b-R1; Beta-R1; betaR1; C-X-C motif chemokine 11; Chemokine (C-X-C motif) ligand 11; Chemokine C-X-C motif ligand 11; CXC11; CXCL11; CXL11_HUMAN; H174; I TAC; I-TAC; Interferon gamma inducible protein 9; Interferon gamma-inducible protein 9; Interferon inducible T cell alpha chemoattractant; Interferon-inducible T-cell a chemoattractant I-TAC; Interferon-inducible T-cell alpha chemoattractant; IP 9; IP-9; IP9; ITAC; MGC102770; SCYB11; SCYB9B; Small inducible cytokine B11; Small inducible cytokine subfamily B (Cys-X-Cys) member 11; Small inducible cytokine subfamily B (Cys-X-Cys) member 9B; Small inducible cytokine subfamily B; member 11; Small inducible cytokine subfamily B; member 9B; Small-inducible cytokine B11

Function

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders

Product Specifications

Recombinant Human C-X-C motif chemokine 11 protein (CXCL11) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 22-94aa, with Tag-Free tag, molecular weight 8.3 kDa, purity >97% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses

Subcellular Location

Secreted

Tissue Specificity

High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders

Subunit

Interacts with TNFAIP6 (via Link domain)

Gene: CXCL11  |  Organism: Homo sapiens  |  Synonyms: Beta-R1; H174; Interferon gamma-inducible protein 9; Interferon-inducible T-cell alpha chemoattractant; Small-inducible cytokine B11
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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