Function
Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).
Biological Context
Subcellular Location: Secreted
Product Specifications
Recombinant Human C-X-C motif chemokine 6 protein (CXCL6), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 43-114aa, with Tag-Free tag, molecular weight 7.9 kDa, purity >98% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications. Explore more Chemokine proteins →
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is in a concentration range of 10- 50 ng/ml.
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.