Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-SUMO-tagged, 29.1kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3), partial

Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3), partial — Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playin…

SKU: BCRECP-000336 Category:
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Product Specifications

Product SkuBCRECP-000336
Product DescriptionRecombinant Human Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 35-155aa. [Accession | P40198].
Uniprot No.P40198
Gene NamesCEACAM3
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region35-155aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight29.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)
Tissue Specificity: CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney

Product Specifications

Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 35-155aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 29.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis

Subcellular Location

Membrane (Single-pass type I membrane protein)

Tissue Specificity

CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney

Subunit

Interacts with S100A9/calprotectin. This interaction is calcium-dependent, but independent of CEACAM3 phosphorylation

Gene: CEACAM3  |  Organism: Homo sapiens  |  Synonyms: Carcinoembryonic antigen CGM1; Carcinoembryonic antigen-related cell adhesion molecule 3
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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