Recombinant Human Biglycan (BGN), Homo sapiens (Human), E.coli, N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged, 57.2kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Biglycan (BGN)

Recombinant Human Biglycan (BGN) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >90%.

SKU: BCRECP-000159 Category:
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Product Specifications

Product SkuBCRECP-000159
Product DescriptionRecombinant Human Biglycan (BGN) Protein is expressed from E.coli with N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. It contains 38-368aa. [Accession | P21810].
Uniprot No.P21810
Gene NamesBGN
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region38-368aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
Molecular weight57.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

May be involved in collagen fiber assembly.

Biological Context

Subcellular Location: Secreted, extracellular space, extracellular matrix
Tissue Specificity: Detected in placenta (at protein level). Found in several connective tissues, especially in articular cartilages
Disease Association: Meester-Loeys syndrome (MRLS) : An X-linked, thoracic aortic aneurysm syndrome characterized by early-onset, severe aortic aneurysm and dissection. Other recurrent findings include hypertelorism, pectus deformity, joint hypermobility, contractures, and mild skeletal dysplasia. [The disease is caused by variants affecting the gene represented in this entry] | Spondyloepimetaphyseal dysplasia, X-linked (SEMDX) : An X-linked recessive bone disease characterized by severe short-trunk dwarfism, brachydactyly, metaphyseal flaring of lower extremities, short and broad long bone diaphyses, moderate platyspondyly, normal facies, and normal intelligence. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Biglycan (BGN) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 38-368aa, with N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged tag, molecular weight 57.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

May be involved in collagen fiber assembly

Subcellular Location

Secreted, extracellular space, extracellular matrix

Disease Association

Meester-Loeys syndrome (MRLS) : An X-linked, thoracic aortic aneurysm syndrome characterized by early-onset, severe aortic aneurysm and dissection. Other recurrent findings include hypertelorism, pectus deformity, joint hypermobility, contractures, and mild skeletal dysplasia. [The disease is caused by variants affecting the gene represented in this entry] | Spondyloepimetaphyseal dysplasia, X-linked (SEMDX) : An X-linked recessive bone disease characterized by severe short-trunk dwarfism, brachydactyly, metaphyseal flaring of lower extremities, short and broad long bone diaphyses, moderate platyspondyly, normal facies, and normal intelligence. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Detected in placenta (at protein level) (PubMed:32337544). Found in several connective tissues, especially in articular cartilages

Subunit

Homodimer. Forms a ternary complex with MFAP2 and ELN (By similarity)

Gene: BGN  |  Organism: Homo sapiens  |  Synonyms: Bone/cartilage proteoglycan I; PG-S1
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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