Recombinant Human Clathrin heavy chain 2 (CLTCL1), partial, Homo sapiens (Human), E.coli, N-terminal 6xHis-tagged, 20.8kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Clathrin heavy chain 2 (CLTCL1), partial

Recombinant Human Clathrin heavy chain 2 (CLTCL1), partial — Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Purity >90%.

SKU: BCRECP-000386 Category:
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Product Specifications

Product SkuBCRECP-000386
Product DescriptionRecombinant Human Clathrin heavy chain 2 (CLTCL1) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 1423-1566aa. [Accession | P53675].
Uniprot No.P53675
Gene NamesCLTCL1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1423-1566aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight20.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.

Biological Context

Subcellular Location: Cytoplasmic vesicle membrane (Peripheral membrane protein); Membrane, coated pit (Peripheral membrane protein)
Tissue Specificity: Maximal levels in skeletal muscle. High levels in heart and testis. Low expression detected in all other tissues

Product Specifications

Recombinant Human Clathrin heavy chain 2 (CLTCL1), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1423-1566aa, with N-terminal 6xHis-tagged tag, molecular weight 20.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network (By similarity)

Subcellular Location

Cytoplasmic vesicle membrane (Peripheral membrane protein); Membrane, coated pit (Peripheral membrane protein)

Tissue Specificity

Maximal levels in skeletal muscle. High levels in heart and testis. Low expression detected in all other tissues

Subunit

Clathrin triskelions, composed of 3 heavy chains and 3 light chains, are the basic subunits of the clathrin coat (By similarity). In the presence of light chains, hub assembly is influenced by both the pH and the concentration of calcium (Probable). May interact with OCRL (By similarity). Interacts with AFTPH/aftiphilin (PubMed:15758025)

Gene: CLTCL1  |  Organism: Homo sapiens  |  Synonyms: Clathrin heavy chain on chromosome 22
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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