Recombinant Human Claudin-18.2 (CLDN18.2)-Detergent (Active)

SKU: BCACP-000310 Category:
Product SKUBCACP-000310
Product DescriptionRecombinant Human Claudin-18.2 (CLDN18.2)-Detergent protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 1-261aa. [Accession | P56856-2].
Uniprot No.P56856-2
Gene NamesCLDN18.2
PurityGreater than 80% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region1-261aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight29.1 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human TGFB3 at 2 μg/mL can bind Human TGFBR2. The EC50 is 6.173-7.152 ng/mL.;Human TGFBR2 captured on Protein A Chip can bind Recombinant Human TGFB3 with an affinity constant of 1.92 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative Names(CLDN18.2)

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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