Function
Required for the formation of the gastric paracellular barrier via its role in tight junction formation, thereby involved in the response to gastric acidification.
Product Specifications
Recombinant Human Claudin-18.2 (CLDN18.2)-Detergent (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 1-261aa, with C-terminal 10xHis-tagged tag, molecular weight 29.1 kDa, purity Greater than 80% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.
Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human TGFB3 at 2 μg/mL can bind Human TGFBR2. The EC50 is 6.173-7.152 ng/mL.;Human TGFBR2 captured on Protein A Chip can bind Recombinant Human TGFB3 with an affinity constant of 1.92 nM as detected by MetaSPR Assay (WeSPRTM 200).
Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.
