Recombinant Human Claudin-18.2 (CLDN18.2)-VLPs, Fluorescent (Active), Homo sapiens (Human), Mammalian cell, C-terminal mCherry-tagged, 52.3 kDa
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Recombinant Human Claudin-18.2 (CLDN18.2)-VLPs, Fluorescent (Active)

Recombinant Human Claudin-18.2 (CLDN18.2)-VLPs, Fluorescent (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell.

SKU: BCACP-000230 Categories: ,
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Product SKUBCACP-000230
Product DescriptionRecombinant Human Claudin-18.2 (CLDN18.2)-VLPs, Fluorescent protein is expressed from Mammalian cell with C-terminal mCherry-tagged. It contains 1-261aa. [Accession | P56856].
Uniprot No.P56856
Gene NamesCLDN18.2
Expression SystemMammalian cell
Expression Region1-261aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal mCherry-tagged
Molecular weight52.3 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human CD70 at 2 μg/mL can bind Anti-CD70 antibody, the EC50 is 2.414-3.196 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative Names(CLDN18.2)

Function

Required for the formation of the gastric paracellular barrier via its role in tight junction formation, thereby involved in the response to gastric acidification.

Biological Context

Subcellular Location: Cell junction, tight junction; Lateral cell membrane
Tissue Specificity: Expression is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level)

Product Specifications

Recombinant Human Claudin-18.2 (CLDN18.2)-VLPs, Fluorescent (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 1-261aa, with C-terminal mCherry-tagged tag, molecular weight 52.3 kDa. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD70 at 2 μg/mL can bind Anti-CD70 antibody, the EC50 is 2.414-3.196 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Required for the formation of the gastric paracellular barrier via its role in tight junction formation, thereby involved in the response to gastric acidification

Subcellular Location

Cell junction, tight junction; Lateral cell membrane

Tissue Specificity

Expression is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level)

Subunit

Interacts with CLDN19

Gene: CLDN18  |  Organism: Homo sapiens
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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