Function
Also has a significant activity in oxidation of tazarotenic acid and may therefore metabolize that xenobiotic in vivo.
Biological Context
Subcellular Location: Endoplasmic reticulum membrane (Peripheral membrane protein); Microsome membrane (Peripheral membrane protein)
Tissue Specificity: Highly expressed in brain, particularly in the cerebellum and pons
Disease Association: Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA) : A disease characterized by craniofacial malformations, occipital encephalocele, radiohumeral fusions, oligodactyly, advanced osseous maturation, and calvarial mineralization defects. [The disease is caused by variants affecting the gene represented in this entry]
Product Specifications
Recombinant Human Cytochrome P450 26B1 (CYP26B1) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-512aa, with N-terminal 6xHis-tagged tag, molecular weight 63.5kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
