Recombinant Human Cytokine receptor-like factor 2 (CRLF2), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 26.8kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Cytokine receptor-like factor 2 (CRLF2), partial (Active)

Recombinant Human Cytokine receptor-like factor 2 (CRLF2), partial (Active) — Receptor for thymic stromal lymphopoietin (TSLP). Purity >95%.

SKU: BCRECP-000427 Category:
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Product Specifications

Product SkuBCRECP-000427
Product DescriptionRecombinant Human Cytokine receptor-like factor 2 (CRLF2) Protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 25-231aa. [Accession | Q9HC73].
Uniprot No.Q9HC73
Gene NamesCRLF2
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region25-231aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight26.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells

Product Specifications

Recombinant Human Cytokine receptor-like factor 2 (CRLF2), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 25-231aa, with C-terminal 10xHis-tagged tag, molecular weight 26.8kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2 (By similarity). Implicated in the development of the hematopoietic system

Subcellular Location

Secreted

Tissue Specificity

Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells

Subunit

Heterodimer of CRLF2 and IL7R

Gene: CRLF2  |  Organism: Homo sapiens  |  Synonyms: Cytokine receptor-like 2; IL-XR; Thymic stromal lymphopoietin protein receptor
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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