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Recombinant Human cytomegalovirus Viral interleukin-10 homolog (UL111A)

Recombinant Human cytomegalovirus Viral interleukin-10 homolog (UL111A) — Functional viral IL-10 homolog. Purity >90%.

Product Specifications

Product SkuBCRECP-004677
Product DescriptionRecombinant Human cytomegalovirus Viral interleukin-10 homolog (UL111A) Protein is expressed from E.coli with Tag-Free. It contains 26-176aa. [Accession | F5HC71].
Uniprot No.F5HC71
Gene NamesUL111A
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region26-176aa
SpeciesHuman cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Tag InfoTag-Free
Molecular weight17.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Human cytomegalovirus Viral interleukin-10 homolog (UL111A) is a recombinant protein from Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5), expressed in E.coli, covering amino acids 26-176aa, with Tag-Free tag, molecular weight 17.5kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells (By similarity)

Subcellular Location

Secreted

Subunit

Homodimer; disulfide-linked

Gene: UL111A  |  Organism: Human cytomegalovirus (strain Merlin)

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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