Recombinant Human DDB1- and CUL4-associated factor 7 (DCAF7)

Recombinant Human DDB1- and CUL4-associated factor 7 (DCAF7) — Involved in craniofacial development. Purity >85%.

SKU: BCRECP-000475 Category:

Product Specifications

Product SkuBCRECP-000475
Product DescriptionRecombinant Human DDB1- and CUL4-associated factor 7 (DCAF7) Protein is expressed from E.coli with N-terminal 10xHis-tagged. It contains 1-342aa. [Accession | P61962].
Uniprot No.P61962
Gene NamesDCAF7
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-342aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged
Molecular weight45.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches.

Biological Context

Subcellular Location: Cytoplasm; Nucleus
Pathway: Protein modification; protein ubiquitination

Product Specifications

Recombinant Human DDB1- and CUL4-associated factor 7 (DCAF7) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-342aa, with N-terminal 10xHis-tagged tag, molecular weight 45.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex

Subcellular Location

Cytoplasm; Nucleus

Subunit

Interacts with DYRK1A, DYRK1B and DIAPH1. Interacts with DDB1. Interacts with ZNF703. Interacts with human adenovirus 5 E1A protein (PubMed:23864635)

Pathway

Protein modification; protein ubiquitination

Gene: DCAF7  |  Organism: Homo sapiens  |  Synonyms: WD repeat-containing protein 68; WD repeat-containing protein An11 homolog
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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