Recombinant Human Delta-like protein 4 (DLL4), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 55.7 kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Delta-like protein 4 (DLL4), partial (Active)

Recombinant Human Delta-like protein 4 (DLL4), partial (Active) — Involved in the Notch signaling pathway as Notch ligand. Purity >95%.

SKU: BCACP-000387 Category:
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Product SKUBCACP-000387
Product DescriptionRecombinant Human Delta-like protein 4 (DLL4) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 27-524aa. [Accession | Q9NR61].
Uniprot No.Q9NR61
Gene NamesDLL4
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region27-524aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight55.7 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human VSIR at 2 μg/mL can bind Anti-VSIR recombinant antibody . The EC50 is 20.84-22.73 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesDelta-like protein 4; Drosophila Delta homolog 4 (Delta4); DLL4; UNQ1895/PRO4341

Function

Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.

Product Specifications

Recombinant Human Delta-like protein 4 (DLL4), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 27-524aa, with C-terminal 10xHis-tagged tag, molecular weight 55.7 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344)

Gene: DLL4  |  Organism: Homo sapiens

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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