Recombinant Human Elongation factor 1-alpha 1 (EEF1A1), Homo sapiens (Human), E.coli, N-terminal 6xHis-tagged, 54.1kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Elongation factor 1-alpha 1 (EEF1A1)

Recombinant Human Elongation factor 1-alpha 1 (EEF1A1) — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >85%.

SKU: BCRECP-000561 Category:
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Product Specifications

Product SkuBCRECP-000561
Product DescriptionRecombinant Human Elongation factor 1-alpha 1 (EEF1A1) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 1-462aa. [Accession | P68104].
Uniprot No.P68104
Gene NamesEEF1A1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-462aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight54.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

(Microbial infection) Required for the translation of viral proteins and viral replication during human coronavirus SARS-CoV-2 infection.

Biological Context

Subcellular Location: Cytoplasm; Nucleus; Nucleus, nucleolus; Cell membrane

Product Specifications

Recombinant Human Elongation factor 1-alpha 1 (EEF1A1) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-462aa, with N-terminal 6xHis-tagged tag, molecular weight 54.1kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) Required for the translation of viral proteins and viral replication during human coronavirus SARS-CoV-2 infection

Subcellular Location

Cytoplasm; Nucleus; Nucleus, nucleolus; Cell membrane

Subunit

Found in a nuclear export complex with XPO5, EEF1A1, Ran and aminoacylated tRNA (PubMed:12426392, PubMed:12426393). Interacts with PARP1 (PubMed:17177976). Interacts with KARS1 (PubMed:18029264). May interact with ERGIC2 (PubMed:17980171). Interacts with IFIT1 (via TPR repeats 4-7) (By similarity). Interacts with DLC1, facilitating distribution to the membrane periphery and ruffles upon growth factor stimulation (PubMed:19158340). Interacts with ZPR1; the interaction occurs in a epidermal growth factor (EGF)-dependent manner (PubMed:8650580). Interacts with PPP1R16B (PubMed:26497934). Interacts with SPHK1 and SPHK2; both interactions increase SPHK1 and SPHK2 kinase activity (PubMed:18263879). Interacts with guanyl-nucleotide exchange factor EEF1B2 (By similarity). Interacts (via middle-region) with HTATIP2 (via N-terminus); the interaction is direct and competes with EEF1A1 binding to guanyl-nucleotide exchange factor EEF1B2, thereby inhibiting GDP for GTP exchange and reactivation of EEF1A1 (By similarity). Interacts with tRNA (By similarity). Interacts with CEP112 (PubMed:39349455)

Gene: EEF1A1  |  Organism: Homo sapiens  |  Synonyms: Elongation factor Tu; Eukaryotic elongation factor 1 A-1; Leukocyte receptor cluster member 7
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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