Recombinant Human Ephrin type-A receptor 2 (EPHA2), partial, Homo sapiens (Human), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 38.3kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Ephrin type-A receptor 2 (EPHA2), partial

Recombinant Human Ephrin type-A receptor 2 (EPHA2), partial — recombinant protein from Homo sapiens (Human), expressed in E.coli. Purity >85%.

SKU: BCRECP-000594 Category:
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Product Specifications

Product SkuBCRECP-000594
Product DescriptionRecombinant Human Ephrin type-A receptor 2 (EPHA2) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 28-328aa. [Accession | P29317].
Uniprot No.P29317
Gene NamesEPHA2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region28-328aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight38.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

Acts as a receptor for human cytomegalovirus (HCMV) to mediate viral entry and fusion in glioblastoma cells.

Biological Context

Subcellular Location: Cell membrane (Single-pass type I membrane protein); Cell projection, ruffle membrane (Single-pass type I membrane protein); Cell projection, lamellipodium membrane (Single-pass type I membrane protein); Cell junction, focal adhesion
Tissue Specificity: Expressed in brain and glioma tissue and glioma cell lines (at protein level). Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g. skin, intestine, lung, and ovary
Disease Association: Cataract 6, multiple types (CTRCT6) : An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. CTRCT6 includes posterior polar and age-related cortical cataracts, among others. Posterior polar cataract is a subcapsular opacity, usually disk-shaped, located at the back of the lens. Age-related cortical cataract is a developmental punctate opacity restricted to the cortex. The cataract is white or cerulean, increases in number with age, but rarely affects vision. [The disease is caused by variants affecting the gene represented in this entry] | [Overexpressed in several cancer types and promotes malignancy]

Product Specifications

Recombinant Human Ephrin type-A receptor 2 (EPHA2), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 28-328aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 38.3kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Acts as a receptor for human cytomegalovirus (HCMV) to mediate viral entry and fusion in glioblastoma cells

Subcellular Location

Cell membrane (Single-pass type I membrane protein); Cell projection, ruffle membrane (Single-pass type I membrane protein); Cell projection, lamellipodium membrane (Single-pass type I membrane protein); Cell junction, focal adhesion

Disease Association

Cataract 6, multiple types (CTRCT6) : An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. CTRCT6 includes posterior polar and age-related cortical cataracts, among others. Posterior polar cataract is a subcapsular opacity, usually disk-shaped, located at the back of the lens. Age-related cortical cataract is a developmental punctate opacity restricted to the cortex. The cataract is white or cerulean, increases in number with age, but rarely affects vision. [The disease is caused by variants affecting the gene represented in this entry] | [Overexpressed in several cancer types and promotes malignancy]

Tissue Specificity

Expressed in brain and glioma tissue and glioma cell lines (at protein level). Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g. skin, intestine, lung, and ovary

Subunit

(Microbial infection) Interacts with Epstein-Barr virus/HHV-4 glycoprotein L/gL and glycoprotein H/gH heterodimer; this interaction facilitates virus internalization and fusion

Gene: EPHA2  |  Organism: Homo sapiens  |  Synonyms: Epithelial cell kinase; Tyrosine-protein kinase receptor ECK
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

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Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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