Recombinant Human Ephrin type-A receptor 2 (EPHA2F), partial (Active)

Recombinant Human Ephrin type-A receptor 2 (EPHA2F), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000471 Category:
Product SKUBCACP-000471
Product DescriptionRecombinant Human Ephrin type-A receptor 2 (EPHA2F) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 24-534aa. [Accession | P29317].
Uniprot No.P29317
Gene NamesEPHA2
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region24-534aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight57.7 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Human ROBO1 at 2 μg/mL can bind Anti-ROBO1 recombinant antibody .The EC50 is 0.7363-0.9105 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesEphrin type-A receptor 2; EC:2.7.10.1; Epithelial cell kinase; Tyrosine-protein kinase receptor ECKEPHA2; ECK

Function

Acts as a receptor for human cytomegalovirus (HCMV) to mediate viral entry and fusion in glioblastoma cells.

Product Specifications

Recombinant Human Ephrin type-A receptor 2 (EPHA2F), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Human ROBO1 at 2 μg/mL can bind Anti-ROBO1 recombinant antibody .The EC50 is 0.7363-0.9105 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Acts as a receptor for human cytomegalovirus (HCMV) to mediate viral entry and fusion in glioblastoma cells

Subcellular Location

Cell membrane (Single-pass type I membrane protein); Cell projection, ruffle membrane (Single-pass type I membrane protein); Cell projection, lamellipodium membrane (Single-pass type I membrane protein); Cell junction, focal adhesion

Disease Association

Cataract 6, multiple types (CTRCT6) : An opacification of the crystalline lens of the eye that frequently results in visual impairment or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or progressive. CTRCT6 includes posterior polar and age-related cortical cataracts, among others. Posterior polar cataract is a subcapsular opacity, usually disk-shaped, located at the back of the lens. Age-related cortical cataract is a developmental punctate opacity restricted to the cortex. The cataract is white or cerulean, increases in number with age, but rarely affects vision. [The disease is caused by variants affecting the gene represented in this entry] | [Overexpressed in several cancer types and promotes malignancy]

Tissue Specificity

Expressed in brain and glioma tissue and glioma cell lines (at protein level). Expressed most highly in tissues that contain a high proportion of epithelial cells, e.g. skin, intestine, lung, and ovary

Subunit

(Microbial infection) Interacts with Epstein-Barr virus/HHV-4 glycoprotein L/gL and glycoprotein H/gH heterodimer; this interaction facilitates virus internalization and fusion

Gene: EPHA2  |  Organism: Homo sapiens  |  Synonyms: Epithelial cell kinase; Tyrosine-protein kinase receptor ECK
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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