Recombinant Human Etoposide-induced protein 2.4 homolog (EI24) Protein, Homo sapiens (Human), in vitro E.coli expression system, N-terminal 6xHis-tagged, 39.8kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human Etoposide-induced protein 2.4 homolog (EI24) Protein

Recombinant Human Etoposide-induced protein 2.4 homolog (EI24) Protein — Acts as a negative growth regulator via p53-mediated apoptosis pathway. Purity >90%.

SKU: BCRECP-00514TM Category:
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Product Specifications

Uniprot No.O14681
Gene NamesEI24
PurityGreater than 90% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region2-340aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight39.8kDa
ActivityNot Test
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy.

Biological Context

Subcellular Location: Nucleus membrane (Multi-pass membrane protein); Cytoplasm; Endoplasmic reticulum membrane (Multi-pass membrane protein)
Disease Association: [EI24 is on a chromosomal region frequently deleted in solid tumors, and it is thought to play a role in breast and cervical cancer. Particularly, expression analysis of EI24 in cancerous tissues shows that EI24 loss is associated with tumor invasiveness]

Product Specifications

Recombinant Human Etoposide-induced protein 2.4 homolog (EI24) Protein is a recombinant protein from Homo sapiens (Human), expressed in in vitro E.coli expression system, covering amino acids 2-340aa, with N-terminal 6xHis-tagged tag, molecular weight 39.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not Test

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity)

Subcellular Location

Nucleus membrane (Multi-pass membrane protein); Cytoplasm; Endoplasmic reticulum membrane (Multi-pass membrane protein)

Disease Association

[EI24 is on a chromosomal region frequently deleted in solid tumors, and it is thought to play a role in breast and cervical cancer. Particularly, expression analysis of EI24 in cancerous tissues shows that EI24 loss is associated with tumor invasiveness]

Subunit

Interacts with BCL2

Gene: EI24  |  Organism: Homo sapiens  |  Synonyms: p53-induced gene 8 protein
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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