Recombinant Human FERM, ARHGEF and pleckstrin domain-containing protein 2 (FARP2), partial, Homo sapiens (Human), E.coli, C-terminal 6xHis-tagged, 40.3kDa, purity >90% as determined by SDS-PAGE.

Recombinant Human FERM, ARHGEF and pleckstrin domain-containing protein 2 (FARP2), partial

Recombinant Human FERM, ARHGEF and pleckstrin domain-containing protein 2 (FARP2), partial — Functions as a guanine nucleotide exchange factor that activates RAC1. Purity >90%.

SKU: BCRECP-000634 Category:
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Product Specifications

Product SkuBCRECP-000634
Product DescriptionRecombinant Human FERM, ARHGEF and pleckstrin domain-containing protein 2 (FARP2) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 44-324aa. [Accession | O94887].
Uniprot No.O94887
Gene NamesFARP2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region44-324aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight40.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

Functions as a guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.

Product Specifications

Recombinant Human FERM, ARHGEF and pleckstrin domain-containing protein 2 (FARP2), partial is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 44-324aa, with C-terminal 6xHis-tagged tag, molecular weight 40.3kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Functions as a guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity)

Subunit

Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding. Interacts with RAC1 (By similarity)

Gene: FARP2  |  Organism: Homo sapiens  |  Synonyms: FERM domain-including RhoGEF; FERM, RhoGEF and pleckstrin domain-containing protein 2; Pleckstrin homology domain-containing family C member 3
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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