Recombinant Human Fibroblast growth factor 21 protein (FGF21), Homo sapiens (Human), E.Coli, Tag-Free, 19.4 kDa, purity >>96% as determined by SDS-PAGE.
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Recombinant Human Fibroblast growth factor 21 protein (FGF21)

Recombinant Human Fibroblast growth factor 21 protein (FGF21) — Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Purity >96%.

SKU: BCACP-000921 Categories: ,
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Product SKUBCACP-000921
Product DescriptionRecombinant Human Fibroblast growth factor 21 protein (FGF21) protein is expressed from E.Coli with Tag-Free. It contains 29-209aa. [Accession | Q9NSA1].
Uniprot No.Q9NSA1
Gene NamesFGF21
Purity>96% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region29-209aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight19.4 kDa
ActivityFully biologically active when compared to standard. The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 cells is less than 0.4 μg/ml, corresponding to a specific activity of >2500 IU/mg in the presence of 15 ng/ml of rHuIGF-II.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesFGF 21; FGF-21; Fgf21; FGF21_HUMAN; FGFL; Fibroblast growth factor 21; PRO10196; UNQ3115

Function

Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.

Product Specifications

Recombinant Human Fibroblast growth factor 21 protein (FGF21) — Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Purity >96%. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 cells is less than 0.4 μg/ml, corresponding to a specific activity of >2500 IU/mg in the presence of 15 ng/ml of rHuIGF-II.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity

Subcellular Location

Secreted

Subunit

Interacts (via C-terminus) with KLB; this interaction is direct. Interacts with FGFR4

Gene: FGF21  |  Organism: Homo sapiens
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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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