Recombinant Mouse Fibroblast growth factor 21 (Fgf21), Mus musculus (Mouse), E.coli, N-terminal 6xHis-tagged, 23.9kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Mouse Fibroblast growth factor 21 (Fgf21)

Recombinant Mouse Fibroblast growth factor 21 (Fgf21) — Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Purity >90%.

SKU: BCRECP-002730 Categories: ,
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Product Specifications

Product SkuBCRECP-002730
Product DescriptionRecombinant Mouse Fibroblast growth factor 21 (Fgf21) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 29-210aa. [Accession | Q9JJN1].
Uniprot No.Q9JJN1
Gene NamesFgf21
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region29-210aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-tagged
Molecular weight23.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity probably requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Most abundantly expressed in the liver, also expressed in the thymus at lower levels. Expressed in skeletal muscle (at protein level). Secreted in plasma (at protein level)

Product Specifications

Recombinant Mouse Fibroblast growth factor 21 (Fgf21) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 29-210aa, with N-terminal 6xHis-tagged tag, molecular weight 23.9kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity probably requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity

Subcellular Location

Secreted

Tissue Specificity

Most abundantly expressed in the liver, also expressed in the thymus at lower levels (PubMed:10858549, PubMed:30389664). Expressed in skeletal muscle (at protein level). Secreted in plasma (at protein level) (PubMed:30605666)

Subunit

Interacts (via C-terminus) with KLB; this interaction is direct. Interacts with FGFR4 (By similarity)

Gene: Fgf21  |  Organism: Mus musculus

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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