Recombinant Human Fms-related Tyrosine Kinase 3 Ligand (FLT3LG), partial (Active) (GMP), Homo sapiens (Human), E.Coli, Tag-Free, 17.6 kDa, purity >> 98 % by SDS-PAGE and HPLC analyses.
, ,

Recombinant Human Fms-related Tyrosine Kinase 3 Ligand (FLT3LG), partial (Active) (GMP)

Recombinant Human Fms-related Tyrosine Kinase 3 Ligand (FLT3LG), partial (Active) (GMP) — Stimulates the proliferation of early hematopoietic cells by activating FLT3. Purity > 98 % by SDS-PAGE and HPLC analyses..

SKU: BCACP-001112 Categories: , ,
Online Inquiry →
Product SKUBCACP-001112
Product DescriptionRecombinant Human Fms-related Tyrosine Kinase 3 Ligand (FLT3LG), (GMP) protein is expressed from E.Coli with Tag-Free. It contains 27-181aa. [Accession | P49771].
Uniprot No.P49771
Gene NamesFLT3LG
Purity> 98 % by SDS-PAGE and HPLC analyses.
Expression SystemE.Coli
Expression Region27-181aa
SpeciesHomo sapiens (Human)
Tag InfoTag-Free
Molecular weight17.6 kDa
ActivityMeasured in a cell proliferation assay using NIH3T3 mouse embryonic fibroblast cells. The ED50 for this effect is ≤2.0 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesFL; Flt 3 ligand; Flt 3L; Flt3 L; FLT3 LG; Flt3 ligand; Flt3L; FLT3L_HUMAN; Flt3lg; Fms related tyrosine kinase 3 ligand; Fms-related tyrosine kinase 3 ligand; SL cytokine

Function

Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. Required for the development of B cells, and dendritic cells (DCs).

Biological Context

Subcellular Location: Secreted
Disease Association: Immunodeficiency 125 (IMD125) : An autosomal recessive immunologic disorder characterized by failure to thrive and chronic diarrhea in infancy, and recurrent bacterial, viral, and fungal infections. Patients have severe human papilloma virus (HPV) infections with disseminated common warts, and the bone marrow is hypoplastic with low levels of CD34+ hematopoietic stem cells. Counts of B cells, monocytes, and dendritic cells are low in patients blood. [The disease may be caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Fms-related Tyrosine Kinase 3 Ligand (FLT3LG), partial (Active) (GMP) is a recombinant protein from Homo sapiens (Human), expressed in E.Coli, covering amino acids 27-181aa, with Tag-Free tag, molecular weight 17.6 kDa, purity > 98 % by SDS-PAGE and HPLC analyses.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured in a cell proliferation assay using NIH3T3 mouse embryonic fibroblast cells. The ED50 for this effect is ≤2.0 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. Required for the development of B cells, and dendritic cells (DCs)

Subcellular Location

Secreted

Disease Association

Immunodeficiency 125 (IMD125) : An autosomal recessive immunologic disorder characterized by failure to thrive and chronic diarrhea in infancy, and recurrent bacterial, viral, and fungal infections. Patients have severe human papilloma virus (HPV) infections with disseminated common warts, and the bone marrow is hypoplastic with low levels of CD34+ hematopoietic stem cells. Counts of B cells, monocytes, and dendritic cells are low in patients blood. [The disease may be caused by variants affecting the gene represented in this entry]

Subunit

Homodimer (isoform 2)

Gene: FLT3LG  |  Organism: Homo sapiens  |  Synonyms: SL cytokine
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top