Recombinant Human Glucose-6-phosphatase catalytic subunit 1 (G6PC1), partial, Homo sapiens (Human), Yeast, C-terminal 6xHis-tagged, 5.6kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Human Glucose-6-phosphatase catalytic subunit 1 (G6PC1), partial

Recombinant Human Glucose-6-phosphatase catalytic subunit 1 (G6PC1), partial — Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Purity >85%.

SKU: BCRECP-000712 Categories: ,
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Product Specifications

Product SkuBCRECP-000712
Product DescriptionRecombinant Human Glucose-6-phosphatase catalytic subunit 1 (G6PC1) Protein is expressed from Yeast with C-terminal 6xHis-tagged. It contains 82-117aa. [Accession | P35575].
Uniprot No.P35575
Gene NamesG6PC1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region82-117aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 6xHis-tagged
Molecular weight5.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.

Biological Context

Subcellular Location: Endoplasmic reticulum membrane (Multi-pass membrane protein)
Disease Association: Glycogen storage disease 1A (GSD1A) : A metabolic disorder characterized by impairment of terminal steps of glycogenolysis and gluconeogenesis. Patients manifest a wide range of clinical symptoms and biochemical abnormalities, including hypoglycemia, severe hepatomegaly due to excessive accumulation of glycogen, kidney enlargement, growth retardation, lactic acidemia, hyperlipidemia, and hyperuricemia. [The disease is caused by variants affecting the gene represented in this entry]
Pathway: Carbohydrate biosynthesis; gluconeogenesis

Product Specifications

Recombinant Human Glucose-6-phosphatase catalytic subunit 1 (G6PC1), partial is a recombinant protein from Homo sapiens (Human), expressed in Yeast, covering amino acids 82-117aa, with C-terminal 6xHis-tagged tag, molecular weight 5.6kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels

Subcellular Location

Endoplasmic reticulum membrane (Multi-pass membrane protein)

Disease Association

Glycogen storage disease 1A (GSD1A) : A metabolic disorder characterized by impairment of terminal steps of glycogenolysis and gluconeogenesis. Patients manifest a wide range of clinical symptoms and biochemical abnormalities, including hypoglycemia, severe hepatomegaly due to excessive accumulation of glycogen, kidney enlargement, growth retardation, lactic acidemia, hyperlipidemia, and hyperuricemia. [The disease is caused by variants affecting the gene represented in this entry]

Pathway

Carbohydrate biosynthesis; gluconeogenesis

Gene: G6PC1  |  Organism: Homo sapiens  |  Synonyms: Glucose-6-phosphatase; Glucose-6-phosphatase alpha
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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