Recombinant Human Glutathione peroxidase 1 (GPX1) (U49S), Homo sapiens (Human), E.coli, N-terminal 6xHis-tagged, 26.1kDa, purity >90% as determined by SDS-PAGE.
,

Recombinant Human Glutathione peroxidase 1 (GPX1) (U49S)

Recombinant Human Glutathione peroxidase 1 (GPX1) (U49S) — Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Purity >90%.

SKU: BCRECP-000782 Categories: ,
Online Inquiry →

Product Specifications

Product SkuBCRECP-000782
Product DescriptionRecombinant Human Glutathione peroxidase 1 (GPX1) (U49S) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 1-203aa(U49S). [Accession | P07203].
Uniprot No.P07203
Gene NamesGPX1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-203aa(U49S)
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-tagged
Molecular weight26.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. In platelets catalyzes the reduction of 12-hydroperoxyeicosatetraenoic acid, the primary product of the arachidonate 12-lipoxygenase pathway.

Biological Context

Subcellular Location: Cytoplasm; Mitochondrion
Tissue Specificity: Expressed in platelets (at protein level)

Product Specifications

Recombinant Human Glutathione peroxidase 1 (GPX1) (U49S) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-203aa(U49S), with N-terminal 6xHis-tagged tag, molecular weight 26.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis (PubMed:11115402, PubMed:36608588). Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides (PubMed:11115402, PubMed:36608588). In platelets catalyzes the reduction of 12-hydroperoxyeicosatetraenoic acid, the primary product of the arachidonate 12-lipoxygenase pathway (PubMed:11115402)

Subcellular Location

Cytoplasm; Mitochondrion

Tissue Specificity

Expressed in platelets (at protein level)

Subunit

Homotetramer. Interacts with MIEN1

Gene: GPX1  |  Organism: Homo sapiens  |  Synonyms: Cellular glutathione peroxidase; Phospholipid-hydroperoxide glutathione peroxidase GPX1
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top