Recombinant Human Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2), Homo sapiens (Human), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 56.7kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2)

Recombinant Human Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) — This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional,… Purity >85%.

SKU: BCRECP-000847 Category:
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Product Specifications

Product SkuBCRECP-000847
Product DescriptionRecombinant Human Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1-449aa. [Accession | P55795].
Uniprot No.P55795
Gene NamesHNRNPH2
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-449aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight56.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).

Biological Context

Subcellular Location: Nucleus, nucleoplasm
Tissue Specificity: Expressed ubiquitously
Disease Association: Intellectual developmental disorder, X-linked, syndromic, Bain type (MRXSB) : A form of intellectual disability, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRXSB patients manifest developmental delay, intellectual disability, autism, hypotonia, seizures, and dysmorphic facial features. Only females are affected. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) is a recombinant protein from Homo sapiens (Human), expressed in E.coli, covering amino acids 1-449aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 56.7kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG)

Subcellular Location

Nucleus, nucleoplasm

Disease Association

Intellectual developmental disorder, X-linked, syndromic, Bain type (MRXSB) : A form of intellectual disability, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRXSB patients manifest developmental delay, intellectual disability, autism, hypotonia, seizures, and dysmorphic facial features. Only females are affected. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Expressed ubiquitously

Subunit

Component of a ribonucleoprotein complex containing mRNAs and RNA-binding proteins including DDX5, HNRNPH2 and SRSF1 as well as splicing regulator ARVCF (PubMed:24644279). Interacts with TXNL4/DIM1 (PubMed:11054566)

Gene: HNRNPH2  |  Organism: Homo sapiens  |  Synonyms: FTP-3; Heterogeneous nuclear ribonucleoprotein H'
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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